Clinical Trials & Research

In a recent study published in the BMC Medicine Journal, researchers conducted a modeling study to evaluate the cost-effectiveness and health impacts of the next-generation vaccines against influenza in Kenya. Image Credit: Riccardo Mayer / Shutterstock Background Influenza is highly prevalent among children below the age of five in Kenya. The recurrent peaks of influenza infections in

Renishaw is pleased to introduce fluorescence lifetime imaging microscopy (FLIM) functionality to its inVia™ confocal Raman microscope. In partnership with Becker & Hickl GmbH, the pioneers in time-correlated single photon counting (TCSPC), the system combines both Raman and FLIM in a single instrument. This integration can overlay both FLIM and Raman images with pixel-to-pixel correlation,

In a recent correspondence article published in the journal Nature Medicine, researchers in the United Kingdom (UK) emphasized the significance of public and patient involvement (PPI) in scientific studies on long coronavirus disease (COVID). Correspondence: Patient and public involvement within epidemiological studies of long COVID in the UK. Image Credit: p.ill.i / Shutterstock Background In 2021, researchers

The glycoprotein V of the blood platelets is an important switch point for hemostasis and thrombus formation. This new finding could have great clinical potential. When our blood vessels are injured by cuts, abrasions, or bruises, it is vital that the bleeding is stopped, and the wound is sealed. This process is called hemostasis and

For over a century, El Paso has long been a sanctuary for individuals suffering from tuberculosis. It will soon be home to groundbreaking research that prevents the debilitating disease. Texas Tech University Health Sciences Center El Paso infectious disease researcher Subramanian Dhandayuthapani, Ph.D., has been awarded a $2.6 million grant from the National Institutes of

Metabolic pathways consist of a series of biochemical reactions in cells that convert a starting component into other products. There is growing evidence that metabolic pathways coupled with external stress factors influence the health of cells and tissues. Many human diseases, including retinal or neurodegenerative diseases, are associated with imbalances in metabolic pathways. Elisabeth Knust

A recent study published in the journal Midwifery evaluated depression, stress, and anxiety in pregnant and postpartum individuals during the coronavirus disease 2019 (COVID-19) pandemic. Study: Depression, Anxiety, and Stress in Pregnancy and Postpartum: A Longitudinal Study During the COVID-19 Pandemic. Image Credit: Mr.Thunman / Shutterstock Background Poor mental health symptoms during pregnancy are associated with a

*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe

A recent study published in The Archives of Italian Urology and Andrology summarized work-related risk factors of male infertility. The World Health Organization (WHO) defines infertility as the inability to achieve pregnancy after one year or more of regular unprotected sexual intercourse. Infertility affects up to 15% of couples; male infertility accounts for a third.

On National Close the Gap Day (Thursday 16 March), Diabetes WA is calling for greater recognition of the disproportionate impact of diabetes on Aboriginal Communities in Western Australia. Aboriginal West Australians are at far greater risk of diabetes and diabetes-related complications than any other community in the State.  Image Credit: Diabetes WA Aboriginal West Australians

With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug combination does not work. Doctors and scientists from the German Cancer Research Center, the Heidelberg Stem Cell Institute HI-STEM and

Patients who have been hospitalized with severe COVID-19 have permanent changes in their cholesterol 3 months after recovery, according to a study from the University of Oslo. This increases their risk of developing heart disease later in life. Many clinicians and scientists have wondered whether COVID-19 disease affects people’s health later in life. Several recent

A Kaiser Permanente study confirms the benefit of nirmatrelvir-ritonavir, also known as Paxlovid, as an early-stage treatment to prevent hospitalization for people with mild to moderate COVID-19, regardless of prior immunity or age. The study was published March 15, 2023, in Lancet ID. Among Kaiser Permanente members in Southern California who tested positive for coronavirus

Whether it’s headaches, abdominal pain, or unrelenting joint soreness, up to a third of young people in Australia experience chronic pain. Image Credit: University of South Australia Now, a world-first study from the University of South Australia is providing valuable insights about how young people understand chronic pain, potentially helping thousands of sufferers to better

Microbiomes have taken on major importance as producers and modulators of the host metabolism and homeostatic machinery. In a new study, researchers at the University of Calgary, Canada, explored the metabolomes of mice exposed to different types of microbes to understand the effects and the possible influences of age and sex on these outcomes. Study:

*Important notice: medRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between

Diagnostic imaging offers physicians and scientists critical visual representations of internal body structures, greatly enhancing clinical analysis and medical intervention. Researchers continue to break new ground on how various imaging technologies can provide a better understanding of human health. Jitao Zhang, assistant professor of biomedical engineering (BME) at Wayne State University and a scientific member

New research in the March 2023 issue of JNCCN-; Journal of the National Comprehensive Cancer Network highlights how the lack of genomic research for people with African ancestry, particularly those from the Sub-Saharan region, is hampering efforts to reduce disparities for people with cancer. In a first-of-its-kind study, the researchers evaluated molecular genetic results for

Pulmonary fibrosis is a devastating disease characterized by progressive scarring in the lungs, killing up to half of patients within five years of a diagnosis. Little is known about whether there are differences in how the condition affects individuals of different ethnicities. New research at the University of Chicago Medicine has found that Black patients

Researchers at Uppsala University in Sweden are using Integra Biosciences’ PIPETBOY pro pipette controllers with integrated LED lighting to study the physiological function of mast cells and their role in allergic reactions. Their ultimate aim is to develop novel vaccines and therapies to prevent and treat common allergies. Image Credit: Integra Biosciences Related Stories The incidence of

The nitrate ingested over the course of a person’s adult lifetime through the consumption of tap water and bottled water could be a risk factor for prostate cancer, particularly in the case of aggressive tumors and in younger men. This is the conclusion of a study conducted in Spain and led by the Barcelona Institute

In a recent study published in the journal Toxicology Letters, researchers discuss the effect(s) of fluoride exposure on the human microbiome. Study: Does fluoride exposure impact on the human microbiome? Image Credit: Photozero / Shutterstock.com The toxicology of fluoride Community water fluoridation (CWF) significantly improves oral health by decreasing the prevalence of caries. The World Health Organization

Compared with men, women continue to have a roughly 30-40 percent higher risk of dying following coronary artery bypass surgery, according to a large study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center. The analysis showed that, without adjusting for differences in age and other health factors that influence risk, the

In a recent study published in the journal Nature, researchers devised a non-invasive optogenetic and wearable cardiac pacemaker for accurate and specific control of cardiac rhythm for ≤900 beats per minute (bpm), enabled by micro-light-emitting display (LED) harness and systemic channelrhodopsin delivery. Studies have reported an increase in heart rate as a result of anxiety. However,

Shine a laser on a drop of blood, mucus, or wastewater, and the light reflecting back can be used to positively identify bacteria in the sample. We can find out not just that bacteria are present, but specifically which bacteria are in the sample – E. coli, Staphylococcus, Streptococcus, Salmonella, anthrax, and more. Every microbe

*Important notice: medRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information. In a recent study posted to the medRxiv* preprint server, researchers examined predictors for hospitalization due to respiratory syncytial virus (RSV) infections to develop a clinical model

Festo introduces the DHOP closed-loop pipette head for high-speed robotic pipetting applications requiring consistent volumes over a wide range of liquid viscosities. The DHOP pipette head provides the utmost in automation flexibility, speed, and feedback when devices handle many liquids. The DHOP closed-loop pipette head provides the utmost in automation flexibility, speed, and feedback when

Recent advances in newborn heart surgery have greatly reduced brain injuries in infants with congenital heart disease, according to a 20-year study by scientists at UCSF Benioff Children’s Hospitals and British Columbia Children’s Hospital (BCCH). The study, begun in 2001 and published this month in the Journal of the American College of Cardiology, analyzed brain